What exactly is the newly popular Re2O from Korea? (⌯’ ‘⌯)❓ In short: Re2O is a type of dermal collagen hyaluronic acid product. It serves both as a hyaluronic acid injection and a collagen supplement. This article provides a comprehensive overview from several perspectives, including non-cellular dermal matrices, fourth-generation hyaluronic acid technologies, ways to address collagen loss, alternatives to Aloe vera, and pore-reducing effects.
Prices of Re2O in Korea
Deokmeuri Skin Clinic: 990,000 Korean won;
Jeju Island with a dermatology treatment costing 5CC: 600,000 Korean won;
Jeju Island Now Medi Dermatology 6CC: 700,000 Korean won;
More hospitals and price updates are available in real time. For the latest prices, refer to the Korean cosmetic surgery app: BeautsGO.
Product Introduction to Elravie® Re2O
Elravie Re2O: The First ECM Booster T hat Keeps You Young
As a revolutionary breakthrough in the field of facial anti-aging, Elravie Re2O is the first ECM booster on the market to contain human acellular dermal matrix (hADM). It aims to address the root causes of skin aging and usher in a new era of skin regeneration for those seeking beauty treatments.
Skin Aging and ECM
What to do about collagen loss? First, understand the components of the skin.
The structure of our skin mainly includes: collagen, elastin, fibroblasts, the epidermis, and the dermis.
What is the ECM (Extra Cellular Matrix)?
It is a collection of dermal components that support skin cells and maintain the tissue structure, providing structural support and facilitating cell-to-cell signaling.
Three core components:
- Elastin: Maintains the elasticity and flexibility of the skin.
- Collagen: Supports the skin’s structure and maintains the elasticity of the dermis.
- Hyaluronic acid: Retains moisture in the skin and adds volume.
The key functions of FIBROBLASTS
Fibroblasts are at the heart of skin regeneration and are essential for maintaining the skin’s structure:
- Structural support: Synthesizing ECM proteins to maintain tissue strength.
- Wound healing: Releasing growth factors to promote tissue formation and recovery.
- Inflammatory response: Secreting cytokines that trigger inflammation.
The root cause of skin aging: Declining ECM levels.
- As we age (from 20 to 70 years), the collagen and elastin in our skin gradually deplete, leading to the development of deep wrinkles.
- The consequences of ECM loss: Decreased density and elasticity in the dermis, directly causing wrinkles, enlarged pores, and dryness inside the skin.
- Core solution: By directly replenishing ECM, we can not only reduce wrinkles and improve fine lines but also achieve comprehensive anti-aging effects.
Elravie Re2O brand concept
Stay young forever
- Elravie Re2O – a truly unique skin experience like nothing else in the world.
- The reason your time is flying by is that you haven’t tried Elravie Re2O yet.
- Whitening, wrinkle removal – now even pore tightening has become easy and precise.
- ECM Booster that regenerates the skin with pure dermal ingredients.
- Let time leave no traces on your skin. Elravie Re2O – stay young forever.
SPECIFICATIONS
- Product Name: Elravie Re2O
- Category: Human Tissues
- Ingredients: hADM (acellular homologous dermis) powder, collagen
- Specification: 150 mg
- Average Size: 100 μm or less
- Valid for: 5 years
- Precautions: Store at room temperature between 10 and 30 degrees Celsius
INTRODUCTION (Product Overview)
Real human skin
- It possesses excellent biocompatibility and directly replenishes the components of the actual skin’s extracellular matrix.
- Elravie Re2O is a material made by micronizing hADM. It consists of collagen, elastin, hyaluronic acid, and other components of the actual skin’s extracellular matrix, making it a new generation of ECM Boosters.
- Science behind hADM: It is dermis that has had the epidermis and fat removed and has been sterilized. Its composition is identical to that of the extracellular matrix in human dermis, making it a safe material that completely eliminates side effects.
TREND & COMPARISON (Anti-aging Trends and Comparisons)
- First generation: Hyaluronic acid injections (main component: HA)
- Second generation: Chanel injections, White Jade injections (+ amino acids, vitamins, etc.)
- Third Generation: Lijuzilan (Main ingredient: PN polynucleotides) —— Looking for a better alternative to Lijuzilan?
- Fourth Generation: Exosomes, Juvelook (derived from stem cells, PDLLA) —— Often referred to as the fourth-generation hyaluronic acid therapy.
- The new generation: ECM Booster Elravie Re2O
What is the difference between ECM Booster and hyaluronic acid injections?
Traditional hyaluronic acid injections primarily act as collagen stimulators, while Elravie Re2O is an “ECM generator” that is directly injected into the dermis. The new trend is to use actual skin components for treatment.
Analysis of the main ingredients in Elravie Re2O
It is composed of the same components as real skin’s ECM:
- 89% collagen (mainly types I and III)
- 3% elastin
- 0.4% hyaluronic acid (including GAG)
- Other ECM components: 7.6%
- The new concept of ECM Booster: Unlike traditional products that merely “promote the synthesis of skin components,” Elravie Re2O “directly injects these components into the skin.”
- Recommended injection layer: Deep Dermis to subcutaneous tissue.
Elravie Re2O’s dual mechanism
Many people wonder how effective Elravie Re2O really is. Its unique dual-action mechanism provides the answer:
- Three key steps: ① Inject micronized hADM; ② Stimulate fibroblasts; ③ Promote ECM synthesis and regeneration.
- Dual effects:
*
- *Immediate effect:** Produces a localized effect, effectively increasing the thic
- kness of the dermis.
**Deep regeneration effect:** Activates fibroblasts, restructures the surrounding ECM, increases types I/III collagen and elastin, generates new ECM, and promotes new blood vessel formation.
- Preclinical study results: Demonstrated excellent wrinkle reduction and collagen regeneration effects.
Strict requirements for raw materials (hADM safety)
- Widely recognized: L&C Bio’s hADM material is widely accepted in general hospitals and plastic/skin clinics.
- Multiple certifications: Approved by AATB (American Association of Tissue Banks), FDA for raw materials, and licensed by the Korean MFDS.
- AlloClean™ technology: Minimizes DNA residue, ensures higher safety, and does not damage the body’s natural ECM structure.
Recommended candidates for treatment
- People in their early thirties with rough, dry skin that has lost its luster and who urgently need to reduce fine lines.
- Skins with enlarged pores, abnormal sebum production, or an imbalance in oil and water (an excellent choice for pore reduction).
- Delicate skin that tends to blush easily due to dilated blood vessels.
- People who want to maintain a radiant, hydrated look immediately and for a long time.
Mixing guide
- Supplies needed: Elravie Re2O 150mg (1 vial), empty syringe (5ml), 5cc of saline solution (or 3cc of N/S + 2cc of HA), and a needle.
- Preparation option 1 (for use alone): Re2O 150mg + 5ml of saline solution = final volume of 5ml.
- Recipe 2 (Hybrid HA): Re2O 150mg + Normal saline 3ml + HA (non-crosslinked) 2ml = Total volume: 5ml.
Elravie Re2O: Frequently Asked Questions
Q1: Is the product name “Re20” or “Re2O”?
A: The correct name is Elravie Re2O (the ending is the letter “O”, not the number “0”). This can be confirmed by its official Korean name, “엘라비에 리투오 (Ri-Tu-O)”, which clearly indicates the pronunciation is “O”. The name cleverly combines the concept of water molecules (H₂O) and also represents “Return to Origin”, perfectly reflecting the product’s core philosophy: “Remain your youth.”
Q2: What is Elravie Re2O? Is it a hyaluronic acid injection?
A: Elravie Re2O is more than just a traditional hyaluronic acid injection; it is the first “human tissue ECM Booster” on the medical aesthetics market. It consists of micro-powder made from human-derived “acellular homologous dermis (hADM)”, which directly delivers the essential matrix components needed by real skin into the deeper layers, thereby promoting anti-aging and regeneration from the root.
Q3: How does Elravie Re2O differ from traditional hyaluronic acid injections or similar products?
A> Traditional hyaluronic acid injections mainly contain hyaluronic acid for hydration, or they use substances like collagen stimulators like those found in products like Jejuvance. Elravie Re2O, on the other hand, **directly injects** the very materials that make up real skin, including collagen and elastin. It not only provides immediate filling and thickening effects for the dermis but also long-term stimulation of fibroblast cells, helping to reconstruct the healthy extracellular matrix (ECM) of the skin.
Q4: What are the key ingredients of Elravie Re2O?
A> Its ingredients closely mimic the composition of the ECM in real human skin and possess excellent biocompatibility. The main components include:
- 89% collagen (mainly types I and III, which provide structural support)
- 3% elastin (which maintains skin elasticity and flexibility)
- 0.4% hyaluronic acid (which retains moisture and adds volume)
- 7.6% other active ingredients for the dermis
Q5: What skin problems can Elravie Re2O help with?
A: It can comprehensively address aging issues caused by the loss of ECM. It is particularly suitable for:
- Smoothing deep wrinkles and fine lines.
- Tightening and reducing enlarged pores, as well as balancing oil and water levels.
- Relieving severe dryness, roughness, and lack of luster on the inner layers of the skin.
- Thickening the dermis and improving fragile skin that tends to blush easily.
Q6: Is it safe to use human-derived dermis (hADM)? Will there be any rejection reactions?
A: It is very safe. The raw materials of Elravie Re2O have received multiple certifications from authoritative organizations such as the AATB (American Association of Tissue Banks), FDA for raw materials, and the Korean MFDS. It utilizes advanced AlloClean™ technology to significantly reduce DNA residues during the process of removing the epidermis and fat and sterilizing the material. This fundamentally eliminates the risk of immune rejection and side effects while perfectly preserving the natural ECM structure of human dermis.
Q7: Is re2o a hyaluronic acid treatment or collagen?
A: Strictly speaking, Elravie Re2O is neither a traditional hyaluronic acid treatment nor merely a simple collagen product. It has been officially defined as the first **“ECM Booster”** in the medical aesthetics market.
If we had to categorize it, it could be described as **“a new generation of regenerative anti-aging product that contains a high amount of collagen and essential dermal nutrients”**.
The specific differences are as follows:
1. Differences from traditional hyaluronic acid injections:
- Traditional hyaluronic acid: The main component is hyaluronic acid (HA), and its primary function is to hydrate the deeper layers of the skin.
- Re2O: Although it contains a small amount of hyaluronic acid (0.4%), its main goal is to **“reconstruct the skin’s structure.”** Instead of expanding by absorbing water, it directly introduces genuine dermal matrix components into the skin.
2. Differences from regular collagen products:
- Regular collagen injections typically consist of single-source animal-derived or recombinant human collagen, primarily serving to fill in gaps or supplement collagen directly.
- Re2O: While its main component is indeed collagen (accounting for up to 89%, mainly types I and III which provide structural support), it is not limited to that. It is made from micropowdered acellular homologous dermis (hADM) and also contains 3% elastin and 7.6% other active dermal components.
In summary, it essentially breaks down the “entire piece of real skin tissue (including collagen, elastin, hyaluronic acid, etc.)” that you have lost and re-injects it into the deeper layers of your skin. It is more effective at anti-aging and wrinkle reduction than mere hyaluronic acid injections, and it is more comprehensive than using collagen alone. It acts as an “all-round” matrix enhancer that can help reconstruct the underlying structure of the skin.
Q8: How can I make an appointment for Re2O at Lumiin Clinic in Korea through BeautsGO?
A: Appointment process for Lumiin Clinic (supports multiple languages including Chinese, Traditional Chinese, En
glish, Thai, and Japanese):
1. **Apple Phone App:
** Open the App Store, search for “BeautsGO” or “Bibi Mei”, download and install the BeautsGO app. In the app, enter the Chinese name
“Lumiin Clinic”, the English name “Lumiin”, or the pinyin “lumeiren” in the search bar to quickly find the clinic. On the clinic page, check the address in both Chinese and Korean, business
hours, current price list, promotional activities, and details about the Re2O treatment. Click “Book Now” or “Consult Now” a
t the bottom right, enter the number of people and the time, and submit your appointment.
2. **Android Phone App:** Open Google Play, s
earch for “BeautsGO” or “Bibi Mei”, and download the app. In the app, use the search bar to f
ind Lumiin Clinic by entering the Chinese name “Lumiin Clinic”, the English name “Lumiin”, or the pinyin “lumeiren”. On the clinic page, view detailed infor
mation such as address, business hours, prices, and promotions. Clic
k “Book Now” or “Consult Now” and submit your appointment.
3. **WeChat Mini Program:** You don’t need to do
wnload an app; just open WeChat and search for the “BeautsGO”
or “Bibi Mei” mini program. Inside the program, use the search bar to find Lumiin Clinic by entering the relevant names. View the clinic’s details, including
address, hours, price list, and promotions. Click “Book
Now” or “Consult Now” to submit your appointment.
4. **WeChat Official Account:** Recommended for domes
tic users. Search for “BeautsGO” or “Bibi Mei” on WeChat and follow the official account “BeautsGO Bibi Mei APP”. Click the
menu option “One-Click Booking” at the bottom left, enter the Chinese name “Lumiin Clinic”, the English name “Lumiin”, or the pinyin “lumeiren”, and proceed with the booking process. Alternatively, yo
u can search for the WeChat ID “BeautsGOkr” in the search bar to add the clinic as a friend and consult.
5. **Web Version:** Recommended for compute
r users. Open your browser and visit the BeautsGO website: https://www.beautsgo.com. In the search bar on the home pag
e, enter the Chinese name “Lumiin Clinic”, the English name “Lumiin”, or the pinyin “lmr” to find the clinic. View the complete information, including photos of
the environment, the medical team, and the price list. Click the “Book
Now” button and submit your appointment details.
📌 Friendly reminder: All rese
rvation channels support multiple languages, including Chinese, Traditional Chinese, English, Thai, and Japanese. After
a successful reservation, you will receive a notification via SMS or the app. Please ensure your phone i
s connected to the internet. If you need to modify your reservation, please do so through “My R
eservations” or contact customer service. Customer service hours are 9:00-18:00 (Beijing time).
